Ralf Morgenstern Selected Research

Neoplasms (Cancer)

10/2023	Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma.
1/2023	Microsomal glutathione transferase 1 in cancer and the regulation of ferroptosis.
1/2023	A role for microsomal glutathione transferase 1 in melanin biosynthesis and melanoma progression.
1/2020	A review on mPGES-1 inhibitors: From preclinical studies to clinical applications.
12/2016	Catalytic Conversion of Lipophilic Substrates by Phase constrained Enzymes in the Aqueous or in the Membrane Phase.
1/2016	Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells.
4/2014	Absence of MGST1 mRNA and protein expression in human neuroblastoma cell lines and primary tissue.
10/2011	Characterization of new potential anticancer drugs designed to overcome glutathione transferase mediated resistance.
9/2011	Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy.
5/2011	Microsomal glutathione transferase 1: mechanism and functional roles.

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Ralf Morgenstern Research Topics

Disease

12	Neoplasms (Cancer) 10/2023 - 02/2007
9	Inflammation (Inflammations) 01/2020 - 07/2006
5	Cataract (Cataracts) 07/2017 - 02/2010
4	Asthma (Bronchial Asthma) 01/2012 - 08/2008
2	Melanoma (Melanoma, Malignant) 10/2023 - 01/2023
2	Myocardial Infarction 10/2012 - 08/2009
2	Fever (Fevers) 09/2007 - 07/2006
2	Pain (Aches) 09/2007 - 07/2006
1	Neoplasm Metastasis (Metastasis) 10/2023
1	Hemorrhage 01/2020
1	Neuroblastoma 04/2014
1	Breast Neoplasms (Breast Cancer) 01/2014
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2011
1	Carcinogenesis 09/2007
1	Anorexia 09/2007
1	Stroke (Strokes) 09/2007
1	Atherosclerosis 09/2007
1	Acquired Immunodeficiency Syndrome (AIDS) 03/2007

Drug/Important Bio-Agent (IBA)

8	Glutathione Transferase (Glutathione S-Transferase)IBA 10/2023 - 02/2007
6	EnzymesIBA 01/2023 - 12/2010
4	AntioxidantsIBA 01/2023 - 01/2011
4	O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfateIBA 12/2016 - 02/2007
3	Dinoprostone (PGE2)FDA Link 01/2020 - 01/2016
3	Cytostatic AgentsIBA 10/2011 - 02/2007
2	CytokinesIBA 10/2023 - 09/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 08/2008
2	Prostaglandins EIBA 12/2019 - 09/2007
2	Prostaglandin-E SynthasesIBA 01/2016 - 09/2010
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2014 - 10/2011
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 03/2013 - 02/2010
2	Glutathione (Reduced Glutathione)IBA 12/2010 - 07/2006
2	Membrane Proteins (Integral Membrane Proteins)IBA 08/2008 - 07/2006
1	microsomal glutathione S-transferase-IIBA 10/2023
1	Glutathione PeroxidaseIBA 10/2023
1	SeleniumIBA 10/2023
1	Melanins (Melanin)IBA 01/2023
1	Levodopa (L Dopa)FDA LinkGeneric 01/2023
1	dopachromeIBA 01/2023
1	Adenosine Triphosphate (ATP)IBA 01/2023
1	eumelaninIBA 01/2023
1	LipidsIBA 01/2020
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2020
1	Vitamin B Complex (B Vitamins)IBA 07/2017
1	Octoxynol (Triton X 100)IBA 12/2016
1	ProdrugsIBA 01/2016
1	Biomarkers (Surrogate Marker)IBA 08/2014
1	Proteins (Proteins, Gene)FDA Link 04/2014
1	Messenger RNA (mRNA)IBA 04/2014
1	PolyestersIBA 01/2014
1	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2013
1	VitaminsIBA 03/2013
1	Coffee FDA Link 10/2012
1	Cisplatin (Platino)FDA LinkGeneric 10/2011
1	Superoxide DismutaseIBA 01/2011
1	Carotenoids (Carotene)IBA 01/2011
1	LeukotrienesIBA 12/2010
1	Leukotriene C4IBA 12/2010
1	ProstaglandinsIBA 09/2010
1	Peroxidase (Myeloperoxidase)IBA 08/2009
1	Formaldehyde (Formol)FDA Link 03/2009
1	AllergensIBA 08/2008
1	Immunoglobulin E (IgE)IBA 08/2008
1	Air Pollutants (Pollutants, Air)IBA 08/2008
1	Phospholipids (Phosphatides)FDA LinkGeneric 03/2007
1	XenobioticsIBA 03/2007
1	EicosanoidsIBA 07/2006

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 01/2016 - 02/2007
1	Immunotherapy 10/2023
1	Cataract Extraction 08/2014
1	Hormone Replacement Therapy (Therapy, Hormone Replacement) 02/2010